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Detection & Physical Characterization of Individual Molecules with Single Nanometer-Scale Pores

Event Details

Event Dates: 

Monday, August 1, 2016 - 3:00pm

Seminar Location: 

  • JILA X317

Speaker Name(s): 

John Kasianowicz

Speaker Affiliation(s): 

NIST, Gaithersburg
Seminar Type/Subject

Scientific Seminar Type: 

  • JILA Public Seminar

Event Details & Abstract: 

Protein-based nanometer-scale pores, which control the traffic of ions across cell membranes, provide the molecular basis of action in nerve, muscle, and other tissues.  We have been developing nanopores for the detection, characterization, identification, and quantitation of individual molecules.  We will discuss the use of these methods for practical applications, including DNA sequencing, single molecule “mass spectrometry”, force spectroscopy, polymer temperature-jump studies, and the identification of proteins and other biomarkers.