TY - JOUR
AU - E. Potma
AU - D. Jones
AU - J.-X. Cheng
AU - X. Xie
AU - Jun Ye
AB - We demonstrate a significant improvement in signal-to-noise ratio in coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two highly synchronized picosecond Ti:sapphire lasers. A temporal jitter between the pulse trains from the two independent commercial lasers is reduced from a few picoseconds to ~21 fs , maintained over several hours. The tight synchronization brings the fluctuation of the CARS signal down to the shot-noise limit, leading to enhanced CARS vibrational images of living cells and polymer beads.

© 2002 Optical Society of America
BT - Optics Letters
DA - 2002-07
DO - 10.1364/OL.27.001168
N2 - We demonstrate a significant improvement in signal-to-noise ratio in coherent anti-Stokes Raman scattering (CARS) spectroscopy/microscopy, using two highly synchronized picosecond Ti:sapphire lasers. A temporal jitter between the pulse trains from the two independent commercial lasers is reduced from a few picoseconds to ~21 fs , maintained over several hours. The tight synchronization brings the fluctuation of the CARS signal down to the shot-noise limit, leading to enhanced CARS vibrational images of living cells and polymer beads.

© 2002 Optical Society of America
PY - 2002
EP - 1168
T2 - Optics Letters
TI - High-sensitivity coherent anti-Stokes Raman scattering microscopy with two tightly synchronized picosecond lasers
VL - 27
SN - 0146-9592
ER -